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Marcia Castro applies geographical information systems, remote sensing, and spatial statistics to her research. She has done extensive work mapping the Brazilian Amazon, and creating a GIS for all of Brazil. Dr. Castro also works on the Dar es Salaam Urban Malaria Control Program, promoting the use of environmental management approaches to improve urban health. Her work also focuses on issues of human mobility and asymptomatic malaria infections in the Brazilian Amazon, as well as on the potential impacts of extreme climatic events on malaria transmission in the Amazon.